Immunohistochemistry: Roots and review

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Abstract

As a well-established discipline, immunohistochemistry has evolved by applying concepts in immunology, hematology, and microbiology to histologic techniques. During the past 30 years, immunohistochemistry has progressed from a novel idea in research to a widely accepted adjunct to the routine histologic work-up of tissues and cytologic preparations. Immunohistochemistry is useful in assessing prognosis, monitoring organ transplants, determining the stage of tumors, establishing the phenotype of lymphomas, and providing clues to a patient's probable response to therapy. The technique also has widespread application in pharmaceutical and cancer research.

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APA

Macrea, E. R. (1999). Immunohistochemistry: Roots and review. Laboratory Medicine. American Society of Clinical Pathologists. https://doi.org/10.1093/labmed/30.12.787

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