Multivesicular assemblies as real-world testbeds for embryogenic evolutionary systems

Abstract

Embryogenic evolution emulates in silico cell-like entities to get more powerful methods for complex evolutionary tasks. As simulations have to abstract from the biological model, implicit information hidden in its physics is lost. Here, we propose to use cell-like entities as a real-world in vitro testbed. In analogy to evolutionary robotics, where solutions evolved in simulations may be tested in real-world on macroscale, the proposed vesicular testbed would do the same for the embryogenic evolutionary tasks on mesoscale. As a first step towards a vesicular testbed emulating growth, cell division, and cell differentiation, we present a modified vesicle production method, providing customtailored chemical cargo, and present a novel self-assembly procedure to provide vesicle aggregates of programmable composition. © Springer-Verlag Berlin Heidelberg 2009.