Background: Hospital-based series have characterized Hafnia alvei primarily as an infrequent agent of polymicrobial nosocomial infections in males with underlying illness. Methods: We conducted population-based laboratory surveillance in the Calgary Health Region during 2000-2005 to define the incidence, demographic risk factors for acquisition, and anti-microbial susceptibilities of Hafnia alvei isolates. Results: A total of 138 patients with Hafnia alvei isolates were identified (2.1/100,000/year) and two-thirds were of community onset. Older age and female gender were important risk factors for acquisition. The most common focus of isolation was urine in 112 (81%), followed by lower respiratory tract in 10 (7%), and soft tissue in 5 (4%), and the majority (94; 68%) were monomicrobial. Most isolates were resistant to ampicillin (111;80%), cephalothin (106; 77%), amoxicillin/clavulanate (98; 71%), and cefazolin (95; 69%) but none to imipenem or ciprofloxacin. Conclusion: Hafnia alvei was most commonly isolated as a mono-microbial etiology from the urinary tract in women from the community. This study highlights the importance of population-based studies in accurately defining the epidemiology of an infectious disease. © 2006 Laupland et al; licensee BioMed Central Ltd.
CITATION STYLE
Laupland, K. B., Church, D. L., Ross, T., & Pitout, J. D. D. (2006). Population-based laboratory surveillance of Hafnia alvei isolates in a large Canadian health region. Annals of Clinical Microbiology and Antimicrobials, 5. https://doi.org/10.1186/1476-0711-5-12
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