A Bayesian approach for false positive reduction in CTC CAD

Abstract

This paper presents an automated detection method for identifying colonic polyps and reducing false positives (FPs) in CT images. It formulates the problem of polyp detection as a probability calculation through a unified Bayesian statistical model. The polyp likelihood is modeled with a combination of shape and intensity features. A second principal curvature PDE provides a shape model; and the partial volume effect is considered in modeling of the polyp intensity distribution. The performance of the method was evaluated on a large multi-center dataset of colonic CT scans. Both qualitative and quantitative experimental results demonstrate the potential of the proposed method. © 2011 Springer-Verlag.