Crystal structure and hydrogen bonding study of (10E)-2,2-dimethyl-3,4- dihydro-2H-benzo[g]chromene-5,10-dione 10-oxime derived from α-Lapachone

Abstract

The compound (10E)-2,2-dimethyl-3,4-dihydro-2H-benzo[g]chromene-5,10- dione-10-oxime (1) was synthesized from a-lapachone and hydroxylamine chloride in alkaline medium. Single-crystals suitable for X-ray diffraction measurements were grown from an ethanol solution, and the crystal structure of the title molecule is reported for the first time. The title molecule was also characterized by 1H- and 13C-NMR in CDCl3 solution, FTIR and MS. The crystal structure of 1 shows an E stereochemistry and dimers formed through classical hydrogen bonds. © 2011.