C-Reactive Protein as The Predictor of Mortality for COVID-19 Patients in Indonesia

0Citations
Citations of this article
14Readers
Mendeley users who have this article in their library.

Abstract

Coronavirus Disease 2019 (COVID-19) confirmed cases and deaths continue to rise. When a virus infects the body, the immune system tries to eliminate the virus. C-Reactive Protein (CRP) is a substance produced in the body in response to infection and inflammation. The study aimed to determine the role of CRP in predicting COVID-19 patients' mortality. From the 1st of March to the 31st of August 2020, data on patients confirmed with COVID-19 were collected from medical records. The correlation between CRP levels and patient mortality was determined using a Chi-Square test. A Receiver Operator Curve (ROC) analysis was used to determine the best CRP cut-off point, and a survival analysis was used to assess the patient outcome. This study included a total of 210 eligible patients. Survivors and non-survivors were divided into two groups of patients (159 patients and 51 patients, respectively). The CRP cut-off was 54 mg/L, with an AUC of 0.817 (p<0.001). C-reactive protein levels were related to COVID-19 patient mortality (p=0.000). According to the survival analysis, patients with CRP levels > 54 mg/L had a lower chance of 30-day survival (p=0.0001). This study presented that CRP levels can be used to predict mortality in COVID-19 patients.

Cite

CITATION STYLE

APA

Afifah, A. R., Liana, P., Fertilita, S., Salim, N. A., Verdiansah, Hilda, F., … Umar, T. P. (2023). C-Reactive Protein as The Predictor of Mortality for COVID-19 Patients in Indonesia. Indonesian Journal of Clinical Pathology and Medical Laboratory, 29(2), 180–184. https://doi.org/10.24293/ijcpml.v29i2.1997

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free