A suggestive case of metastatic disease from breast cancer is reported. The HER-2-positive tumor was refractory to several agents, including anti-HER-2 therapy, trastuzumab, and lapatinib. After re-induction of trastuzumab in combination with activated natural killer (NK) cell injection therapy, tumor markers decreased, and finally a synergistic effect of taxane and capecitabine led to treatment response. This case suggests that multidisciplinary therapy including an immunological approach might be a breakthrough in the treatment of refractory disease. © 2010 The Japanese Breast Cancer Society.
CITATION STYLE
Takada, M., Terunuma, H., Deng, X., Dewan, M. Z., Saji, S., Kuroi, K., … Toi, M. (2011). Refractory lung metastasis from breast cancer treated with multidisciplinary therapy including an immunological approach. Breast Cancer, 18(1), 64–67. https://doi.org/10.1007/s12282-010-0198-5
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