Comparison of a novel, rapid chromogenic biochemical assay, the carba NP test, with the modified hodge test for detection of carbapenemase-producing gram-negative bacilli

Abstract

We compared carbapenemase detection among 271 Gram-negative bacilli (of which 131 were carbapenemase producers) using a novel chromogenic rapid test-the Carba NP test (CNP)-and the modified Hodge test (MHT). Sensitivities were comparable (CNP, 100%, versus MHT, 98%; P=0.08), but CNP was more specific (100% versus 80%; P<0.0001) and faster. Copyright © 2013, American Society for Microbiology. All Rights Reserved.