MUC5AC levels associated with respiratory syncytial virus disease severity

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Abstract

To assess MUC5AC as a biomarker for respiratory syncytial virus (RSV) disease severity, we tested nasal aspirates from RSV+ children with mild, moderate, and severe disease. Levels were significantly higher in those in the severe and moderate groups compared to mild group, indicating MUC5AC may be a useful biomarker for RSV disease severity.

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Rajan, D., O’Keefe, E. L., Travers, C., McCracken, C., Geoghegan, S., Caballero, M. T., … Anderson, L. J. (2018). MUC5AC levels associated with respiratory syncytial virus disease severity. Clinical Infectious Diseases, 67(9), 1441–1444. https://doi.org/10.1093/cid/ciy340

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