Better Understanding the Immunopathogenesis of Psoriasis

Abstract

1 Abstract The immunopathogenesis of psoriasis involves complex interactions between the innate and the adap-tive immune system, with emphasis on participation of keratinocytes, neutrophils, dermal dendritic cells and T lymphocytes.The knowledge of the immunopathogen-esis of the disease is essential for understanding the mechanism of action of several systemic medications used in the treatment of the disease, especially the bio-logics.In this article the main and current knowledge of the immunopathogenesis of psoriasis is summarised.