Unusual direction of three-component reactions involving 2-amino-4-arylimidazoles and carbonyl compounds leading to Knoevenagel-Michael adducts

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Abstract

Three-component reaction of 2-amino-4-arylimidazoles, aldehydes and dimedone or barbituric acid proceeds in an unusual direction and instead of imidazo[1,2-a]pyrimidine derivatives gives Knoevenagel-Michael adducts having abnormally low reactivity in heterocyclizations. © ARKAT-USA, Inc.

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Andriushchenko, A. Y., Saraev, V. E., Shishkina, S. V., Shishkin, O. V., Musatov, V. I., Desenko, S. M., & Chebanov, V. A. (2013). Unusual direction of three-component reactions involving 2-amino-4-arylimidazoles and carbonyl compounds leading to Knoevenagel-Michael adducts. Arkivoc, 2013(3), 61–80. https://doi.org/10.3998/ark.5550190.0014.306

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