Tissue tolerable plasma and polihexanide: Are synergistic effects possible to promote healing of chronic wounds? in Vivo and in Vitro results

Abstract

The assumption is that tissue tolerable plasma works as promoter for wound healing and can be beneficially combined with the antiseptic polihexanide to avoid bacterial recolonization. The effects of a combined plasma - polihexanide (PHMB) application on cell integrity, cytotoxicity and its irritative and inflammative potential were tested in vitro and in two dogs in vivo. © 2012 Springer Science+Business Media B.V.