To assess the genetic factors contributing to daptomycin resistance in Staphylococcus aureus, the draft genome of a clinically derived daptomycin-nonsusceptible isolate APS211 was generated and compared to the draft sequence of its susceptible progenitor strain APS210. Four genetic differences were identified including a previously described mutation within the mprF gene.
CITATION STYLE
Cameron, D. R., Jiang, J. H., Abbott, I. J., Spelman, D. W., & Peleg, A. Y. (2015). Draft genome sequences of clinical daptomycin-nonsusceptible methicillin-resistant Staphylococcus aureus strain APS211 and its daptomycin-susceptible progenitor APS210. Genome Announcements, 3(3). https://doi.org/10.1128/genomeA.00568-15
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