Abstract
Clinical trial methodology in SSc is evolving and has been improving. This chapter reviews updated aspects of clinical trials such as epidemiology, phases of trial design, outcome measures, surrogate measures, patient selection, analysis, and updated guidelines for trial design.
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APA
Suliman, Y. A., Agrawal, H., & Furst, D. E. (2016). Clinical trial design in systemic sclerosis. In Scleroderma: From Pathogenesis to Comprehensive Management (pp. 623–635). Springer International Publishing. https://doi.org/10.1007/978-3-319-31407-5_46
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