Distinctive spinal changes in two patients with unusual forms of autosomal dominant endosteal hyperostosis: A case series

Abstract

Endosteal hyperostosis was encountered in a 26-year-old-man and his 6-month-old daughter. Both the father and his daughter presented with fractures. Odontoid process hyperplasia, and progressive sclerosis of the posterior spinal elements, was the other significant features. To the best of our knowledge, this is the first clinical report describing distinctive spinal changes in association with fractures and endosteal hyperostosis. © 2007 Al Kaissi et al; licensee BioMed Central Ltd.