Isogenic iPSC-derived models of disease

  • Niemitz E
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Abstract

The use of patient-derived induced pluripotent stem cells (iPSCs) to study genetic mechanisms of disease has been limited by the confounding effect of genetic background. Now, Rudolf Jaenisch, Rajesh Ambasudhan, Stuart Lipton and colleagues report the use of isogenic iPSC-derived models of a dominant familial form of Parkinson's disease to…

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Niemitz, E. (2014). Isogenic iPSC-derived models of disease. Nature Genetics, 46(1), 7–7. https://doi.org/10.1038/ng.2864

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