A research proposal testing a new model of ambulation activity among long-term care residents with dementia/cognitive impairment: The study protocol of a prospective longitudinal natural history study

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Abstract

Background: Excessive and patterned ambulation is associated with falls, urinary tract infections, co-occurring delirium and other acute events among long-term care residents with cognitive impairment/dementia. This study will test a predictive longitudinal data model that may lead to the preservation of function of this vulnerable population. Methods/design: This is a single group, longitudinal study with natural observations. Data from a real-time locating system (RTLS) will be used to objectively and continuously measure ambulation activity for up to 2 years. These data will be combined with longitudinal acute event and functional status data to capture patterns of change in health status over time. Theory-driven multilevel models will be used to test the trajectories of falls and other acute conditions as a function of the ambulation activity and demographic, functional status, gait quality and balance ability including potential mediation and/or moderation effects. Data-driven machine learning algorithms will be applied to run screening of the high dimensional RTLS data together with other variables to discover new and robust predictors of acute events. Discussion: The findings from this study will lead to the early identification of older adults at risk for falls and the onset of acute medical conditions and interventions for individualized care.

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Bowen, M. E., Rowe, M. A., Ji, M., & Cacchione, P. (2019). A research proposal testing a new model of ambulation activity among long-term care residents with dementia/cognitive impairment: The study protocol of a prospective longitudinal natural history study. BMC Research Notes, 12(1). https://doi.org/10.1186/s13104-019-4585-5

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