Multimodality monitoring correlates of seizures

Abstract

Continuous EEG (cEEG) in critically ill patients has shown a high incidence of electrographic seizures, but the underlying pathophysiology is unclear and the aggressiveness of management controversial. Increasing use of invasive multimodality monitoring (MMM) provides a window into the brain physiology in real time. Insights into the pathophysiologic underpinnings of seizures may provide valuable information to better characterize these post-injury phenomena. In this chapter, following a brief review of different components, methods, and devices of MMM, we summarize the existing knowledge of MMM measures during seizures and other epileptiform patterns. We discuss these findings in the context of surface EEG (sEEG) and intracortical/depth EEG (dEEG) recordings. Lastly we highlight potential questions for future investigations.