Rare mutations in the VHL gene may lead to polycythemia in children. Ruxolitinib resulted in clinical improvement in three people with this disorder.
CITATION STYLE
Zhou, A. W., Knoche, E. M., Engle, E. K., Ban-Hoefen, M., Kaiwar, C., & Oh, S. T. (2016). Clinical Improvement with JAK2 Inhibition in Chuvash Polycythemia. New England Journal of Medicine, 375(5), 494–496. https://doi.org/10.1056/nejmc1600337
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