Degenerative pleomorphic adenoma of the nasal cavity

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Introduction: Malignant salivary gland tumor usually involves the parotid gland. Although unusual locations have been reported for such tumors, we here report an extremely rare case of nasal location in a salivary gland adenoma with malignant transformation. Observation: A 65-year-old man with diabetes and hypertension presented with left nasosinal tumefaction causing nasal obstruction with slow evolution and recent onset of epistaxis and slight telecanthus. CT, MRI and nasosinal bone biopsy were performed. Treatment was by surgical exeresis on an external approach. Conclusion: Malignant transformation of a pleomorphic adenoma with nasal location is extremely rare and little described in the literature. Imaging found strong signs of malignancy, confirmed on histology. Surgical exeresis was the only effective treatment option. © 2010 Elsevier Masson SAS. All rights reserved.




Yazibene, Y., Ait-Mesbah, N., Kalafate, S., Yahi-Ait Mesbah, N., Abdennebi, A., Bouzid, H., & Kalem, K. (2011). Degenerative pleomorphic adenoma of the nasal cavity. European Annals of Otorhinolaryngology, Head and Neck Diseases, 128(1), 37–40.

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