Multifaced roles of PLAC8 in cancer

18Citations
Citations of this article
24Readers
Mendeley users who have this article in their library.

Abstract

The role of PLAC8 in tumorigenesis has been gradually elucidated with the development of research. Although there are common molecular mechanisms that enforce cell growth, the impact of PLAC8 is varied and can, in some instances, have opposite effects on tumorigenesis. To systematically understand the role of PLAC8 in tumors, the molecular functions of PLAC8 in cancer will be discussed by focusing on how PLAC8 impacts tumorigenesis when it arises within tumor cells and how these roles can change in different stages of cancer progression with the ultimate goal of suppressing PLAC8-relevant cancer behavior and related pathologies. In addition, we highlight the diversity of PLAC8 in different tumors and its functional output beyond cancer cell growth. The comprehension of PLAC8’s molecular function might provide new target and lead to the development of novel anticancer therapies.

Cite

CITATION STYLE

APA

Mao, M., Cheng, Y., Yang, J., Chen, Y., Xu, L., Zhang, X., … Wang, L. (2021, December 1). Multifaced roles of PLAC8 in cancer. Biomarker Research. BioMed Central Ltd. https://doi.org/10.1186/s40364-021-00329-1

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free