Arterial PaO2 and PaCO2 influence seizure duration in dogs receiving electroconvulsive therapy

22Citations
Citations of this article
18Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

The influence of arterial O2 and CO2 tensions on electroconvulsive seizure duration was investigated in five mongrel dogs under consistent anaesthetic conditions. Seizure durations were measured in a randomized protocol of nine possible combinations of arterial gas tension spanning increased, normal or decreased levels of PaO2 and PaCO2. Seizure duration was directly related to PaO2 (p < 0.00001) and inversely related to PaCO2 (p < 0.0001). A significant synergism was evident at the extremes of PaO2 and PaCO2, with seizure duration being greater than predicted for hyperoxia-hypocapnia and hypoxia-hypercapnia and shorter than predicted for hypoxiahypocapnia and hyperoxia-hypercapnia. We conclude that arterial gas tensions strongly influence ECT-induced seizure duration and through this may influence the therapeutic efficacy of electroconvulsive therapy. © 1987 Canadian Anesthesiologists.

Cite

CITATION STYLE

APA

Douglas, C., Butler, P., & Froese, A. (1987). Arterial PaO2 and PaCO2 influence seizure duration in dogs receiving electroconvulsive therapy. Canadian Journal of Anaesthesia, 34(5), 437–441. https://doi.org/10.1007/BF03014344

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free