Ventilation and perfusion matching is optimized for gas exchange. Induction of anesthesia, one-lung ventilation (OLV), and opening of the chest progressively uncouple ventilation-perfusion (V/Q) homeostasis. Hypoxic pulmonary vasoconstriction (HPV) improves V/Q matching during OLV but can be impaired by anesthetic interventions.
CITATION STYLE
McLean, S. R., & Lohser, J. (2019). Physiology of the Lateral Decubitus Position, Open Chest, and One-Lung Ventilation. In Principles and Practice of Anesthesia for Thoracic Surgery: Second Edition (pp. 93–105). Springer International Publishing. https://doi.org/10.1007/978-3-030-00859-8_5
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