Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius

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Abstract

The total flavonoids of Indocalamus latifolius were evaluated in term of their anti-oxidant and hepatoprotective activities. The results showed that in vitro hepatoprotective and anti-oxidant activities of total flavonoids at doses of 200 and 400 mg/kg and 100 mg/kg, respectively, were comparable to those of the known hepatoprotective drug silymarin at 100 mg/kg. These data were supplemented with histopathological studies of rat liver sections. Seven of the main flavonoid compounds purified by column chromatography using silica gel, sephadex LH-20 and develosil ODS, and determined to be vitexin, orientin, isovitexin, homoorientin, tricin, tricin-7-O-β-D-glucopyranoside and quercetin-3-O-glucopyranoside.

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Tan, J., Li, S., Zeng, J., & Wu, X. (2015). Anti-oxidant and hepatoprotective activities of total flavonoids of Indocalamus latifolius. Bangladesh Journal of Pharmacology, 10(4), 779–789. https://doi.org/10.3329/bjp.v10i4.23496

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