Talimogene Laherparepvec

  • Rotte A
  • Bhandaru M
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Abstract

Talimogene laherparepvec (tal im' oh jeen la her" pa rep' vek), often simply called "T-VEC" is a cancer-killing (oncolytic) virus currently being studied for the treatment of melanoma and other advanced cancers. The drug was initially developed by BioVex, Inc. under the name OncoVEXGM-CSF until it was acquired by Amgen in 2011. With the announcement of positive results in March 2013, T-VEC is the first oncolytic virus to be proven effective in a Phase III clinical trial.

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Rotte, A., & Bhandaru, M. (2016). Talimogene Laherparepvec. In Immunotherapy of Melanoma (pp. 333–347). Springer International Publishing. https://doi.org/10.1007/978-3-319-48066-4_14

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