Haemodynamic responses to subconjunctival mydriatic agents (Mydricaine) used for maintenance of perioperative mydriasis in patients undergoing vitreoretinal surgery

Abstract

Purpose. To assess the systemic effects of subconjunctival mydriatic agents (Mydricaine). Methods. Haemodynamic variables were recorded at baseline and during the first 60 min following subconjunctival injection of Mydricaine and normal saline. Results. Statistical analysis of the change in heart rate showed a highly significant difference between the two groups (p < 0.001). There was no significant difference in the effect on systolic or diastolic blood pressure between the two groups. Conclusions. We advise extreme caution when using Mydricaine via the subconjunctival route in patients with compromised cardiac function.