Exercise Training Improves Lipid Profile in the Elderly: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Abstract

The objective of this systematic review and meta-Analysis is to examine the effects of different exercise training on lipid profiles in older adults. A database search was performed (PubMed, Scopus, Web of Science and Google Scholar) to identify controlled clinical trials in English language. The mean difference (MD) with 95% confidence intervals (CIs) and overall effect size were calculated for all comparisons. The PEDro scale was used assess the methodological quality. Thirteen studies were included in the review. The meta-analysis found a significant effect of exercise training on Triglycerides TG in the elderly (difference in means=11.56; Z=2.51; p=0.01; I2 =97%) and a significant effect of exercise training on Total Cholesterol TC in the elderly (difference in means=14.33; Z=4.13; p=0.00; I2 =88%) and a significant effect of exercise training on High-Density Lipoprotein (HDL) in the elderly (difference in means=3.41; Z=2.80; p=0.00; I2=92%) and a significant effect of exercise training on Low-Density Lipoprotein (LDL) in the elderly (difference in means=12.74; Z=3.33; p=0.00; I2=91%). This systematic review and meta-analysis found that the elderly can improved their lipid profiles by participating in aerobic and combined exercise training programs. Further studies on the physiologic effects of exercise training on lipid profiles are needed.