Regulatory framework for hemoglobin-based oxygen carrier trials

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Abstract

Oxygen therapeutics (OT) consist of hemoglobin-based oxygen carriers (HBOCs) and fluorocarbons. They have been developed to deliver oxygen (O2) to tissues, mainly for treatment of shock due to blood loss. These products are being developed in order to treat blood loss when red blood cells are not available, as may occur on the battlefield or in civilian life when trauma occurs.

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Golding, B. (2013). Regulatory framework for hemoglobin-based oxygen carrier trials. In Hemoglobin-Based Oxygen Carriers as Red Cell Substitutes and Oxygen Therapeutics (Vol. 9783642407178, pp. 149–156). Springer-Verlag Berlin Heidelberg. https://doi.org/10.1007/978-3-642-40717-8_9

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