Abstract
Several studies of DNA vaccination against HER2/neu showed the effectiveness of immunization protocols in models of transplantable or spontaneous tumors. The DNA delivery system plays a crucial role in the success of DNA vaccination. In particular, our studies of DNA vaccination against HER2/neu tumor antigen showed that intramuscular injection of the vaccine followed by electroporation elicits an optimal protection against the development of spontaneous HER2/neu- tumors occurring in transgenic mice.
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CITATION STYLE
Smorlesi, A., Papalini, F., Pierpaoli, S., & Provinciali, M. (2008). HER2/neu DNA vaccination for breast tumors. Methods in Molecular Biology (Clifton, N.J.), 423, 473–485. https://doi.org/10.1007/978-1-59745-194-9_37
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