Caracterización de enfermedad metastásica con PET/CT en cáncer de mama en etapificación y con recidiva postratamiento

Abstract

Purpose. To describe metastatic disease detected by PET/CT in breast cancer (BC), and to evaluate the relative contribution of PET and CT analyzed separately. Patients and Method. We defined two groups of patients with BC: 1) recently diagnosed with no treatment, 2) with relapse after treatment. We described findings which are visible exclusively with CT and exclusively with PET. Results. In recently diagnosed patients (n=17) 88% show lymphadenopathies, 29% bone metastases (BM), 17% lung metastases, 17% hepatic metastases, and 11% other localizations. For relapsed patients (n=35) these percentages were 54%, 62%, 34%, 31% and 28%, respectively. CT detected more lung nodules and sclerotic bone lesions than PET. PET detected more lymphadenopathies, medullary bone and hepatic lesions than CT. There were synchronous cancers in 6% of recently diagnosed patients and in 11% of relapsed patients. Conclusion. BC patients show mainly lymph nodal and bone metastasis. The PET/CT hybrid study detected more lesions than PET and CT analyzed separately.