Treatment of Addison’s disease during pregnancy

  • Oliveira D
  • Lages A
  • Paiva S
  • et al.
N/ACitations
Citations of this article
26Readers
Mendeley users who have this article in their library.

Abstract

Addison’s disease, or primary adrenocortical insufficiency, is a long-term, potentially severe, rare endocrine disorder. In pregnancy, it is even rarer. We report the case of a 30-year-old pregnant patient with Addison’s disease, referred to Obstetrics-Endocrinology specialty consult at 14 weeks gestation. She had been to the emergency department of her local hospital various times during the first trimester presenting with a clinical scenario suggestive of glucocorticoid under-replacement (nausea, persistent vomiting and hypotension), but this was interpreted as normal pregnancy symptoms. Hydrocortisone dose was adjusted, and the patient maintained regular follow-up. No complications were reported for the remainder of gestation and delivery. Pregnant patients with Addison’s disease should be monitored during gestation and in the peripartum period by multidisciplinary teams. Adjustments in glucocorticoid and mineralocorticoid replacement therapy are often necessary, and monitoring should be based mainly on clinical findings, which becomes increasingly difficult during pregnancy. Patient education and specialized monitoring are key to avoiding complications from under- or over-replacement therapy in this period.

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Oliveira, D., Lages, A., Paiva, S., & Carrilho, F. (2018). Treatment of Addison’s disease during pregnancy. Endocrinology, Diabetes & Metabolism Case Reports, 2018. https://doi.org/10.1530/edm-17-0179

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 9

64%

Researcher 5

36%

Readers' Discipline

Tooltip

Medicine and Dentistry 9

64%

Engineering 2

14%

Biochemistry, Genetics and Molecular Bi... 2

14%

Nursing and Health Professions 1

7%

Article Metrics

Tooltip
Mentions
News Mentions: 1

Save time finding and organizing research with Mendeley

Sign up for free