Sebaceous metaplasia in a canine mammary gland non-infiltrative carcinoma with myoepithelial component

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Abstract

Sebaceous metaplasia in canine mammary tumors is a rare condition with only 1 case documented. The current study describes a case of sebaceous metaplasia in a mammary gland carcinoma of an 8-year-old intact, nulliparous female Poodle dog with a subcutaneous tumor located in the left fifth mammary gland. The lesion measured 0.7 cm × 0.5 cm × 0.6 cm in diameter, was firm, circumscribed, painless, non-haired, and non-ulcerated, and did not adhere to deep tissues. The cut surface was non-lobulated, non-encapsulated, whitish to gray, and opaque. Histological evaluation revealed 3 different populations of cells: the first was composed of columnar to cuboidal malignant epithelial cells arranged in intraductal papillary projections, the second of myoepithelial cells associated with a myxoid stroma, and the third presenting sebaceous metaplasia similar to those previously described in both human and veterinary medicine. © 2011 American Association of Veterinary Laboratory Diagnosticians.

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Grandi, F., Colodel, M. M., Rocha, R. M., & Sequeira, J. L. (2011). Sebaceous metaplasia in a canine mammary gland non-infiltrative carcinoma with myoepithelial component. Journal of Veterinary Diagnostic Investigation, 23(6), 1230–1233. https://doi.org/10.1177/1040638711425569

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