Hydrogen bonding and concurrent interactions

Abstract

The lecture deals with the various forms of interactions with dominant electrostatic component. It points to dipole/dipole interactions as strong structure determining factor that often accompanies hydrogen bond and halogen bond interactions, and becomes the major structure determining factor when hydrogen bond donor groups are no longer available. It illustrates a combined use of hydrogen bond, halogen bond and dipolar interactions for engineering of reliable layer motifs. © 2008 Springer Netherlands.