The term optic glioma encompasses a diverse group of tumors that can arise anywhere along the visual pathway from the globe to the optic radiations. A particularly challenging subgroup of these tumors involves the hypothalamus in conjunction with the optic chiasm. Because complete resection of such lesions is not feasible without excessive morbidity, a variety of adjuvant management options have been explored. The success of low-intensity outpatient chemotherapy regimens in the treatment of chiasmatic-hypothalamic gliomas has led to dramatic changes in management algorithms for these tumors during the last decade. A second factor that has come to influence management in recent years is the recognition that optic pathway tumors in children with neurofibromatosis type 1 (NF1) typically behave in a substantially more indolent manner than in those without this disorder, necessitating a correspondingly more conservative approach to intervention. © 2010 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Pollack, I. F., & Jakacki, R. I. (2010). Optic gliomas. In Oncology of CNS Tumors (pp. 395–404). Springer Berlin Heidelberg. https://doi.org/10.1007/978-3-642-02874-8_23
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