Abstract
Definition: Multiple or plasma cell myeloma (PCM) is a bone marrow-based multifocal plasma cell neoplasm, usually associated with secretion of a single homogeneous monoclonal immunoglobulin called M protein. The bone marrow is the site of origin of nearly all PCMs. Multifocal bone marrow involvement is frequently observed. In advanced disease, extramedullary involvement can be appreciated.
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Sbaraglia, M. (2019). Multiple Myeloma. In Diagnosis of Musculoskeletal Tumors and Tumor-like Conditions: Clinical, Radiological and Histological Correlations - the Rizzoli Case Archive (pp. 349–353). Springer International Publishing. https://doi.org/10.1007/978-3-030-29676-6_53
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