Background: Antigen specific release of IP-10 is the most promising alternative marker to IFN-γ for infection with M. tuberculosis. Compared to Interferon-γ release assays (IGRA), IP-10 is released in high levels enabling novel approaches such as field friendly dried blood spots (DBS) and molecular detection.
CITATION STYLE
Blauenfeldt, T., Heyckendorf, J., Jensen, S. G., Lange, C., Drabe, C., Hermansen, T. S., … Ruhwald, M. (2014). Development of a one-step probe based molecular assay for rapid immunodiagnosis of infection with M. Tuberculosisusing dried blood spots. PLoS ONE, 9(9). https://doi.org/10.1371/journal.pone.0105628
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