Store-operated Ca2+ channels are plasma membrane channels that are activated by depletion of intracellular Ca2+ stores, resulting in an increase in intracellular Ca2+; however, little is known about their regulation. Our work has shown that the immunosuppressant compound BTP2, which blocks Ca2+ influx into cells, interacts with the actin-reorganizing protein, drebrin. Here we review the role of drebrin in the regulation of calcium signaling, with a focus on immune cells.
CITATION STYLE
Pabon, J., Law, M. K., & August, A. (2017). Drebrin regulation of calcium signaling in immune cells. In Advances in Experimental Medicine and Biology (Vol. 1006, pp. 281–290). Springer New York LLC. https://doi.org/10.1007/978-4-431-56550-5_16
Mendeley helps you to discover research relevant for your work.