Monitoring of cardiac preload by determination of pulmonary artery occlusion pressure (PAOP) has been traditionally used to guide fluid therapy to optimize cardiac output (CO). Since factors such as intrathoracic pressure and ventricular compliance may modify PAOP, volumetric estimators of preload have been developed. The PiCCO system is able to measure CO and intrathoracic blood volume (ITBV) by transpulmonary thermodilution. Aim: To compare a volumetric (ITBV) versus a pressure (PAOP) determination to accurately estimate cardiac preload in severely ill patients. Patients and Methods: From June 2001 to October 2003, 22 mechanically ventilated patients with hemodynamic instability underwent hemodynamic monitoring with pulmonary artery catheter (PAC) and PiCCO system. ITBV index (ITBVI), PAOP and CI were measured simultaneously by both methods. One hundred thirty eight deltas ( ) were obtained from the difference syndrome (ARDS). Delta ITBVI significantly correlated with interval = 0.41-0.65; p <0.01). There was no correlation between of ITBVI, PAOP, CI-PAC and CI-PiCCO between 6-12 am and 6-12 pm. Linear regression analysis of CI-PAC were made. Results: Mean age of patients was 7. Fifteen patients met criteria for acute respiratory distress CI-PiCCO (r=0.54; 95% confidence CI-PAC. Conclusion: ITBVI versus 60.8 CI-PiCCO and PAOP versus 19.4 years. APACHE II was 23.9 PAOP and ITBVI correlated better with CI than PAOP, and therefore it seems to be a more accurate estimator of preload in unstable, mechanically ventilated patients.
CITATION STYLE
Tomicic F, V., Graf S, J., Echevarría O, G., Espinoza R, M., Abarca Z, J., Montes S, J. M., … Canals L, C. (2005). Volumen sanguíneo intratorácico versus presión arterial de oclusión pulmonar como estimadores de precarga cardíaca en pacientes críticos. Revista Médica de Chile, 133(6). https://doi.org/10.4067/s0034-98872005000600001
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