Small Interfering RNAs Targeting a Chromatin-Associated RNA Induce Its Transcriptional Silencing in Human Cells

  • Ouvrard J
  • Muniz L
  • Nicolas E
  • et al.
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Abstract

Transcriptional gene silencing by small interfering RNAs (siRNAs) has been widely described in various species, including plants and yeast. In mammals, its extent remains somewhat debated.

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Ouvrard, J., Muniz, L., Nicolas, E., & Trouche, D. (2022). Small Interfering RNAs Targeting a Chromatin-Associated RNA Induce Its Transcriptional Silencing in Human Cells. Molecular and Cellular Biology, 42(12). https://doi.org/10.1128/mcb.00271-22

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