Two day treatment of trichomoniasis in the female. Comparison of metronidazole and nimorazole

Abstract

A comparison was made of the efficiency of a 2 day course of metronidazole (Flagyl) with that of a similar course of nimorazole (Naxogin) in the treatment of trichomonias. Of the 105 consecutive patients treated, 72 were finally included in the study (38 on metronidazole and 34 on nimorazole). Follow up tests indicated an overall cure rate of 84.3 percent. in those given Flagyl and 85.3 percent. in those given Naxogin. Consorts were treated in just over 55 percent. of cases in both groups. An attempt has been made to classify the recurrences as either primary treatment failures or reinfections. Although both drugs were effective in the majority of cases, primary treatment failure appeared to be commoner in the group receiving metronidazole. It is emphasized that the total dose of metronidazole was substantially lower than that recommended by the manufacturers.