The Effects of Leakage Conductance on Firing Properties in a Compartment Neuron Model

Abstract

See, stats, and : https : / / www . researchgate . net / publication / 265844030 Advances (III) Chapter DOI : 10 . 1007 / 978 - 94 - 007 - 4792 - 0_108 CITATIONS 0 READS 45 2 : Some : job leadership Lei Peking 774 , 906 SEE Liu South 67 SEE All . The . All - text and , letting . Abstract Leakage current is a critical factor which can balance ions flow across channels in neuron . In this study , a simple case is considered about the influence of leakage conductance g L on neuronal firing activities in a two compartment model , the detailed analysis includes two aspects : (1) . the values of g L in the two compartments are equal , (2) . the values of g L in the two compartments are not equal . With computer simulation , it is found that numerical results obtained from the variation of g L in somatic compartment and dendritic compartment show much difference , simulation results obtained from variation of g L in dendritic compartment have much similarity with results got in case (1) when g L varies , while the variation of g L in soma gives some difference with the case in (1) . In the final the changing of membrane capacitance to the potential spike is also discussed here . All these results may give us a general rule of neuronal firing properties .