Tiadinil, a novel class of activator of systemic acquired resistance, induces defense gene expression and disease resistance in tobacco

Abstract

Systemic acquired resistance (SAR) is a potent innate immunity system in plants and effective against a broad range of pathogens. Tiadinil (TDL), N-(3-chloro-4-methylphenyl)-4-methyl-1,2,3-thiadiazole-5-carboxamide, was recently developed to control rice blast disease without direct antimicrobial activity. To clarify the mode of action of TDL, effects of TDL on tobacco plants were investigated. TDL induced resistance against tobacco mosaic virus and tobacco wildfire disease (Pseudomonas syringae pv. tabaci) without antimicrobial activity in tobacco plants. TDL also induced the expression of SAR marker genes. These results indicated that TDL induced SAR in tobacco plants.