Comparative evaluation of the four most commonly used pediatric liquid formulations in Ahmedabad city: An in vitro study

Abstract

Introduction: This study was conducted to assess the cariogenic potential of pediatric liquid medicaments (PLMs) of Allopathic, Homeopathic, Ayurvedic, and Unani formulations specifically in Ahmedabad. Materials and methods: Four commonly used PLMs were selected based on a survey. Thirty-nine exfoliated deciduous teeth samples were placed in selected PLM for 1 minute, 10 minutes, and 8 hours and observed under scanning electron microscope to check the erosive potential. Their endogenous pH, calcium dissolution potential, viscosity, and type and amount of sugar were checked. Results: In all the four groups, a specific type of enamel prism pattern was seen in all the samples irrespective of magnification and immersion time. However, the degree of erosion increases with the increase in immersion time. All the four syrups were acidic in nature. Lowest pH (3.73) and highest calcium dissolution (7.106) were seen in Saduri®. Viscosity was higher with Benadryl® mainly due to high sugar content (36.10), especially glucose (27.21). Conclusion: All the PLMs used in this study showed an erosive effect on the primary enamel surface though major effect was seen with Saduri®. Clinical significance: With respect to this study, Unani medications are most cariogenic for the teeth among all the four types of medications in children.