Overweight and Obesity are Risk Factors of Severe Illness in Patients with COVID-19

40Citations
Citations of this article
180Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

Objective: This study aimed to observe the clinical characteristics of patients with coronavirus disease 2019 (COVID-19) with overweight and obesity. Methods: Consecutive patients with COVID-19 from 10 hospitals of Jiangsu province, China, were enrolled. Results: A total of 297 patients with COVID-19 were included, and 39.39% and 13.47% of patients had overweight and obesity, respectively. The proportions of bilateral pneumonia (92.50% vs. 73.57%, P = 0.033) and type 2 diabetes (17.50% vs. 3.57%, P = 0.006) were higher in patients with obesity than lean patients. The proportions of severe illness in patients with overweight (12.82% vs. 2.86%, P = 0.006) and obesity (25.00% vs. 2.86%, P < 0.001) were significantly higher than lean patients. More patients with obesity developed respiratory failure (20.00% vs. 2.86%, P < 0.001) and acute respiratory distress syndrome (5.00% vs. 0%, P = 0.024) than lean patients. The median days of hospitalization were longer in patients with obesity than lean patients (17.00 days vs. 14.00 days, P = 0.029). Overweight (OR, 4.222; 95% CI: 1.322-13.476; P = 0.015) and obesity (OR, 9.216; 95% CI: 2.581-32.903; P = 0.001) were independent risk factors of severe illness. Obesity (HR, 6.607; 95% CI: 1.955-22.329; P = 0.002) was an independent risk factor of respiratory failure. Conclusions: Overweight and obesity were independent risk factors of severe illness in COVID-19 patients. More attention should be paid to these patients.

Cite

CITATION STYLE

APA

Wang, J., Zhu, L., Liu, L., Zhao, X. an, Zhang, Z., Xue, L., … Wu, C. (2020). Overweight and Obesity are Risk Factors of Severe Illness in Patients with COVID-19. Obesity, 28(11), 2049–2055. https://doi.org/10.1002/oby.22979

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free