Severe cases of SARS-CoV-2 and other pathogenic virus infections are often associated with the uncontrolled release of proinflammatory cytokines, known as a “cytokine storm.” We present a protocol for multiplex analysis of three cytokines, tumor necrosis factor-alpha (TNF-a), interleukin 6 (IL-6), and IL-10, which are typically elevated in cytokine storm events and may be used as a predictive biomarker profile of disease severity or disease course.
CITATION STYLE
Guest, P. C., Abbasifard, M., Jamialahmadi, T., Majeed, M., Kesharwani, P., & Sahebkar, A. (2022). Multiplex Immunoassay for Prediction of Disease Severity Associated with the Cytokine Storm in COVID-19 Cases. In Methods in Molecular Biology (Vol. 2511, pp. 245–256). Humana Press Inc. https://doi.org/10.1007/978-1-0716-2395-4_18
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