Prevalence and Pattern of Bacterial Isolates in Cases of Pelvic Inflammatory Disease Patients at a Tertiary Hospital in Osogbo, Nigeria

Abstract

Abstract: This study was aimed at determining the microbial spectrum from endocervical swab cultures of patients with suspected pelvic inflammatory disease and their in vivo antibiotic sensitivity patterns. Endocervical swabs were collected from 100 patients attending a tertiary health institution in Nigeria. Bacteria isolates were characterized by standard protocol as described by Cowan and Steel and susceptibility tests were performed by Stokes’s technique. Statistical analysis was made by simple percentages among related variables. About 70% of patients were positive for the infection; there were seven microbial organisms isolated with Staphylococcus aureus as the most commonly isolated organism in 41.4% of cases followed by Klebsiella species with (24.29%), Escherichia coli (12.86%), Pseudomonas species (8.57%) and Candida ablicans (12.4%). Only thirteen antibiotic disks were used in testing for sensitivity of the isolated bacteria. Penicillin, ampicillin and tetracycline were the most frequently resistant antibiotics with 71, 52.7 and 71.7% resistance rates. The remaining ten antibiotics had >50% sensitivity rate. Age group 25-30 years were significantly more infected with bacteria than any other age group. Routine screening and treatment of women for lower genital tract infections to minimize their role in PID is recommended.