Evaluating the Feasibility of Hydrogel-Based Neural Cell Sprays

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Neurological injuries have poor prognoses with serious clinical sequelae. Stem cell transplantation enhances neural repair but is hampered by low graft survival ( ca. 80%) and marker expression/proliferative potential of hydrogel-sprayed astrocytes was retained. Combining a cell spray format with polymer encapsulation technologies could form the basis of a non-invasive graft delivery method, offering potential advantages over current cell delivery approaches.




Evans, D., Barcons, A. M., Basit, R. H., Adams, C., & Chari, D. M. (2023). Evaluating the Feasibility of Hydrogel-Based Neural Cell Sprays. Journal of Functional Biomaterials, 14(10). https://doi.org/10.3390/jfb14100527

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