The genetic defects that occur during tumor evolution perturb an intricate web of highly interconnected intracellular and intercellular signaling pathways. These molecular circuits, populated in part by proto-oncogenes and tumor suppressor genes, normally serve to maintain functionally healthy cells and stable tissues.
CITATION STYLE
Bunz, F. (2022). Cancer Gene Pathways. In Principles of Cancer Genetics (pp. 211–280). Springer International Publishing. https://doi.org/10.1007/978-3-030-99387-0_6
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