Medical treatment of ectopic pregnancy

Abstract

Early diagnosis of ectopic pregnancy has allowed medical treatment of this condition with methotrexate. The criteria of methotrexate treatment include hemodynamic stability, ability to comply with follow-up, serum human chorionic gonadotropin (hCG) < 5000 mIU/mL, and absence of fetal cardiac activity. In most women, one dose of intramuscular methotrexate (50 mg/m2 body surface) is effective. Patients can attempt to conceive after serum hCG is undetectable.