Primary angiosarcoma of the breast

Abstract

Primary angiosarcoma of the breast is a rare malignancy, usually affecting young women between the third and fourth decades of life. It is manifested as a palpable, rapidly growing mass in the breast of women with no history of exposure to ionizing radiation. Surgery is the main treatment modality, with the role of radiotherapy and chemotherapy remaining unclear due to a lack of randomized clinical trials. The prognosis of primary angiosarcoma is unfavourable, with a high rate of local recurrence and early haematogenous dissemination, particularly to the lungs, being typical.